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ea0056oc6.4 | Genetic and environmental determinants of obesity and insulin resistance | ECE2018

Anthropometric measurements and metabolic syndrome in relation to glucocorticoid receptor polymorphisms in (local) corticosteroid users

Savas Mesut , Wester Vincent L. , Iyer Anand M. , van den Akker Erica L.T. , van Rossum Elisabeth F.C.

Introduction: Corticosteroids are amongst the most prescribed drugs and their use has been linked to cardiometabolic adverse events including weight gain and abdominal adiposity. We previously showed that users were also more likely to have the metabolic syndrome (MetS). Since an essential role in the pathway of glucocorticoid (GC) action is reserved for the glucocorticoid receptor (GR), it could be proposed that GC sensitivity altering polymorphisms could affect the vulnerabi...

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ea0081p259 | Adrenal and Cardiovascular Endocrinology | ECE2022

Outcome of COVID-19 infections in patients with adrenal insufficiency

Nowotny Hanna , Bryce Jillian , Giordano Roberta , Baronio Federico , Chifu Irina , Cools Martine , van den Akker Erica L.T. , Falhammar Henrik , Appelman-Dijkstra Natasha , Persani Luca , Beccuti Guglielmo , Glasberg Simona , Pereira Alberto M , Sverre Husebye Eystein , Hahner Stefanie , Ahmed Faisal , Reisch Nicole

Background: Only few cases of patients with adrenal disorders affected by coronavirus disease 2019 (COVID-19) have been reported so far. In this study, clinical outcome data of patients with adrenal disorders and COVID-19 infection has been collected by the ESE Rare Disease Committee and ENDO-ERN via the European Registries for Rare Endocrine Conditions (EuRRECa) project.Methods: This questionnaire included 32 questions on collecting quantitative and qua...

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Endocrine Abstracts

Anthropometric measurements and metabolic syndrome in relation to glucocorticoid receptor polymorphisms in (local) corticosteroid users

Outcome of COVID-19 infections in patients with adrenal insufficiency

BiosciAbstracts